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Constitutive Activation of the N-Methyl-d-aspartate Receptor via Cleft-spanning Disulfide Bonds

Although the N-methyl-d-aspartate (NMDA) receptor plays a critical role in the central nervous system, many questions remain regarding the relationship between its structure and functional properties. In particular, the involvement of ligand-binding domain closure in determining agonist efficacy, wh...

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Detalhes bibliográficos
Main Authors: Blanke, Marie L., VanDongen, Antonius M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490796/
https://ncbi.nlm.nih.gov/pubmed/18450751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709190200
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