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Long-range, high-throughput haplotype determination via haplotype-fusion PCR and ligation haplotyping

Ligation Haplotyping is a robust, novel method for experimental determination of haplotypes over long distances, which can be applied to assaying both sequence and structural variation. The simplicity and efficacy of the method for genotyping large chromosomal rearrangements and haplotyping SNPs ove...

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Bibliographic Details
Main Authors: Turner, Daniel J., Tyler-Smith, Chris, Hurles, Matthew E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490767/
https://ncbi.nlm.nih.gov/pubmed/18562465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn373
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