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Minigene-like inhibition of protein synthesis mediated by hungry codons near the start codon
Rare AGA or AGG codons close to the initiation codon inhibit protein synthesis by a tRNA-sequestering mechanism as toxic minigenes do. To further understand this mechanism, a parallel analysis of protein synthesis and peptidyl-tRNA accumulation was performed using both a set of lacZ constructs where...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2490762/ https://ncbi.nlm.nih.gov/pubmed/18583364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn395 |
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