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Dispatched Homolog 2 is targeted by miR-214 through a combination of three weak microRNA recognition sites

MicroRNAs (miRNAs) regulate gene expression by inhibiting translation of target mRNAs through pairing with miRNA recognition elements (MREs), usually in 3′ UTRs. Because pairing is imperfect, identification of bona fide mRNA targets presents a challenge. Most target recognition algorithms strongly e...

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Detalhes bibliográficos
Main Authors: Li, Nan, Flynt, Alex S., Kim, H. Rosemary, Solnica-Krezel, Lilianna, Patton, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490740/
https://ncbi.nlm.nih.gov/pubmed/18583362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn388
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