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Accumulation of GC donor splice signals in mammals

The GT dinucleotide in the first two intron positions is the most conserved element of the U2 donor splice signals. However, in a small fraction of donor sites, GT is replaced by GC. A substantial enrichment of GC in donor sites of alternatively spliced genes has been observed previously in human, n...

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Bibliografske podrobnosti
Main Authors: Churbanov, Alexander, Winters-Hilt, Stephen, Koonin, Eugene V, Rogozin, Igor B
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2490688/
https://ncbi.nlm.nih.gov/pubmed/18613975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-6150-3-30
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