Resistance to human immunodeficiency virus type 1 (HIV-1) infection in human CD4+ lymphocyte-derived cell lines conferred by using retroviral vectors expressing an HIV-1 RNA-specific ribozyme.

Toward gene therapy for the treatment of human immunodeficiency virus type 1 (HIV-1) infections in AIDS, Moloney murine leukemia virus-derived retroviral vectors were engineered to allow constitutive and tat-inducible expression of an HIV-1 5' leader sequence-specific ribozyme (Rz1). These vectors w...

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Pubblicato in:	J Virol
Autori principali:	Weerasinghe, M, Liem, S E, Asad, S, Read, S E, Joshi, S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1991
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC249052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1895402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.10.5531-5534.1991
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