Mutational analysis of the simian immunodeficiency virus SIVmac nef gene.

We are using site-directed mutagenesis of single viral genes to identify and analyze the genetic determinants of human and simian immunodeficiency virus pathogenicity. In a first approach, we have constructed a series of simian immunodeficiency virus SIVmac nef mutants by partial deletion and insert...

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Bibliographic Details
Main Authors: Binninger, D, Ennen, J, Bonn, D, Norley, S G, Kurth, R
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC249002/
https://ncbi.nlm.nih.gov/pubmed/1716690
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