A 15-kilobase-pair region of the human cytomegalovirus genome which includes US1 through US13 is dispensable for growth in cell culture.

The genome of a temperature-sensitive, DNA-negative mutant of human cytomegalovirus was cloned in cosmids and analyzed by restriction endonuclease mapping and Southern blotting. The data presented show that in the mutant genome, nearly half of the short segment was deleted (14.3 to 15.1 kb; map posi...

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Publicado en:J Virol
Autores principales: Kollert-Jöns, A, Bogner, E, Radsak, K
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248995/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1654438/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.10.5184-5189.1991
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