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Cytopathic variants of an attenuated isolate of human immunodeficiency virus type 2 exhibit increased affinity for CD4.

Naturally occurring isolates of human immunodeficiency virus (HIV) have been described which are deficient in their ability to fuse with and kill CD4+ target cells. Although the molecular basis for their attenuation has not yet been defined, several lines of evidence point toward the viral envelope...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Hoxie, J A, Brass, L F, Pletcher, C H, Haggarty, B S, Hahn, B H
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1991
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248977/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1870213/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.9.5096-5101.1991
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