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Transcriptional elongation by purified RNA polymerase II is blocked at the trans-activation-responsive region of human immunodeficiency virus type 1 in vitro.

It has previously been shown that the human immunodeficiency virus type 1 (HIV-1) trans-activation-responsive region (TAR) is contained in a stem-loop RNA structure. Moreover, the interaction of the RNA secondary structure with Tat, the trans-activator protein, seems to play a role in activation of...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Bengal, E, Aloni, Y
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1991
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248952/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1870206/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.9.4910-4918.1991
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