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Ribosomes can slide over and beyond “hungry” codons, resuming protein chain elongation many nucleotides downstream

In cells subjected to moderate aminoacyl-tRNA limitation, the peptidyl-tRNA–ribosome complex stalled at the “hungry” codon can slide well beyond it on the messenger RNA and resume translation further downstream. This behavior is proved by unequivocal amino acid sequence data, showing a protein that...

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Détails bibliographiques
Auteurs principaux: Gallant, Jonathan A., Lindsley, Dale
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC24895/
https://ncbi.nlm.nih.gov/pubmed/9811876
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