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Characterization of large deletions occurring during a single round of retrovirus vector replication: novel deletion mechanism involving errors in strand transfer.

Retroviruses mutate at a high rate during replication. We used a spleen necrosis virus-based vector system and helper cell line to characterize mutations occurring during a single round of retrovirus replication. The vector used, JD216HyNeo, codes for two drug resistance genes, hygromycin resistance...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphov: Pulsinelli, G A, Temin, H M
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 1991
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248936/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1714517/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.9.4786-4797.1991
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