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Characterization of poliovirus 2A proteinase by mutational analysis: residues required for autocatalytic activity are essential for induction of cleavage of eukaryotic initiation factor 4F polypeptide p220.

The poliovirus proteinase 2A is autocatalytically released from the poliovirus polyprotein by cotranslational cleavage at its own amino terminus, resulting in separation of structural and nonstructural protein precursors. Cleavage is a prerequisite for further processing of the structural protein pr...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Hellen, C U, Fäcke, M, Kräusslich, H G, Lee, C K, Wimmer, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248859/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1649327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.8.4226-4231.1991
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