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Intrinsic and Cyclin-dependent Kinase-dependent Control of Spindle Pole Body Duplication in Budding Yeast

Centrosome duplication must be tightly controlled so that duplication occurs only once each cell cycle. Accumulation of multiple centrosomes can result in the assembly of a multipolar spindle and lead to chromosome mis-segregation and genomic instability. In metazoans, a centrosome-intrinsic mechani...

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Detalhes bibliográficos
Main Authors: Simmons Kovacs, Laura A., Nelson, Christine L., Haase, Steven B.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488292/
https://ncbi.nlm.nih.gov/pubmed/18480404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0148
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