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Intrinsic and Cyclin-dependent Kinase-dependent Control of Spindle Pole Body Duplication in Budding Yeast

Centrosome duplication must be tightly controlled so that duplication occurs only once each cell cycle. Accumulation of multiple centrosomes can result in the assembly of a multipolar spindle and lead to chromosome mis-segregation and genomic instability. In metazoans, a centrosome-intrinsic mechani...

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Autori principali: Simmons Kovacs, Laura A., Nelson, Christine L., Haase, Steven B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488292/
https://ncbi.nlm.nih.gov/pubmed/18480404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0148
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