The BMP binding protein Crossveinless 2 is a short-range, concentration-dependent, biphasic modulator of BMP signaling in Drosophila

In Drosophila, the secreted BMP-binding protein Short gastrulation (Sog) inhibits signaling by sequestering BMPs from receptors, but enhances signaling by transporting BMPs through tissues. We show that Crossveinless 2 (Cv-2) is also a secreted BMP-binding protein that enhances or inhibits BMP signa...

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Bibliographic Details
Main Authors: Serpe, Mihaela, Umulis, David, Ralston, Amy, Chen, Jun, Olson, David J., Avanesov, Andrei, Othmer, Hans, O'Connor, Michael B., Blair, Seth S.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488203/
https://ncbi.nlm.nih.gov/pubmed/18539121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.03.023
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