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Genetic instability of cancer cells is proportional to their degree of aneuploidy

Genetic and phenotypic instability are hallmarks of cancer cells, but their cause is not clear. The leading hypothesis suggests that a poorly defined gene mutation generates genetic instability and that some of many subsequent mutations then cause cancer. Here we investigate the hypothesis that gene...

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Autors principals: Duesberg, Peter, Rausch, Charlotte, Rasnick, David, Hehlmann, Ruediger
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC24881/
https://ncbi.nlm.nih.gov/pubmed/9811862
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