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Biochemical Bases for the Antimetabolite Action of l-Serine Hydroxamate
The amino acid analogue l-serine hydroxamate, which is bacteriostatic for Escherichia coli, has been shown to inhibit protein synthesis. The antimetabolite is a competitive inhibitor of seryl-transfer ribonucleic acid (tRNA) synthetase with a K(i) value of 30 μm. Mutants resistant to l-serine hydrox...
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| Publicado no: | J Bacteriol |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1971
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248741/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4934072/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.106.3.972-982.1971 |
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