Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding.

The binding of the CD4 receptor by the human immunodeficiency virus type 1 gp120 exterior envelope glycoprotein is important for virus entry and cytopathic effect. To investigate the CD4-binding region of the gp120 glycoprotein, we altered gp120 amino acids, excluding cysteines, that are conserved a...

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Hauptverfasser: Olshevsky, U, Helseth, E, Furman, C, Li, J, Haseltine, W, Sodroski, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1990
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC248709/
https://ncbi.nlm.nih.gov/pubmed/2243375
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