Impairing follicle-stimulating hormone (FSH) signaling in vivo: Targeted disruption of the FSH receptor leads to aberrant gametogenesis and hormonal imbalance

Pituitary gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone stimulate the gonads by regulating germ cell proliferation and differentiation. FSH receptors (FSH-Rs) are localized to testicular Sertoli cells and ovarian granulosa cells and are coupled to activation of the adenyly...

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Bibliographic Details
Main Authors: Dierich, Andrée, Sairam, M. Ram, Monaco, Lucia, Fimia, Gian Maria, Gansmuller, Anne, LeMeur, Marianne, Sassone-Corsi, Paolo
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC24867/
https://ncbi.nlm.nih.gov/pubmed/9811848
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