Limited internal friction in the rate-limiting step of a two-state protein folding reaction
Small, single-domain proteins typically fold via a compact transition-state ensemble in a process well fitted by a simple, two-state model. To characterize the rate-limiting conformational changes that underlie two-state folding, we have investigated experimentally the effects of changing solvent vi...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1998
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24863/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811844/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.23.13591 |
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