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A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N(4)-ethenocytosine and the G/T mismatch

Etheno adducts in DNA arise from multiple endogenous and exogenous sources. Of these adducts we have reported that, 1,N(6)-ethenoadenine (ɛA) and 3,N(4)-ethenocytosine (ɛC) are removed from DNA by two separate DNA glycosylases. We later confirmed these results by using a gene knockout mouse lacking...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hang, B., Medina, M., Fraenkel-Conrat, H., Singer, B.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24858/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811839/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.23.13561
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