Ablation of NK Cell Function During Tumor Growth Favors Type 2-Associated Macrophages, Leading to Suppressed CTL Generation

Several reports describe regulatory interactions between NK cells and CTLs. We addressed the issue of NK participation in the early anti-tumor defense by inoculating α-ASGM-1 treated mice with BW-Sp3 T lymphoma. Rejection of BW-Sp3 depends on strong CTL responses. Our results demonstrated that (i) N...

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Main Authors: Geldhof, Anja B., van Ginderachter, Jo A., Liu, Yuanqing, Noël, Wim, de Baetselier, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485417/
https://ncbi.nlm.nih.gov/pubmed/14768937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10446670310001626580
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