Variability in the pharmacokinetics of intravenous busulphan given as a single daily dose to paediatric blood or marrow transplant recipients

AIM: To examine inter- and intrapatient variability in the pharmacokinetics of intravenous (i.v.) busulphan given as a single daily dose to children with malignant (n = 19) and nonmalignant (n = 21) disease. METHODS: Busulphan (120 mg m(−2), 130 mg m(−2) or 3.2 mg kg(−1)) was administered over media...

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Detalhes bibliográficos
Main Authors: Nath, Christa E, Earl, John W, Pati, Nalini, Stephen, Katherine, Shaw, Peter J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2008
Assuntos:
Pharmacodynamics and Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485261/
https://ncbi.nlm.nih.gov/pubmed/18341668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03166.x
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