Acute passive cigarette smoke exposure and inhaled human insulin (Exubera®) pharmacokinetics

AIMS: Relative to nonsmokers, the bioavailability of inhaled human insulin (Exubera®; EXU) is markedly increased in chronic smokers. The pharmacokinetics of EXU following passive cigarette smoke exposure is unknown. METHODS: In an open-label, crossover study, healthy nonsmoking volunteers received t...

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Главные авторы: Fountaine, Robert, Milton, Ashley, Checchio, Tina, Wei, Greg, Stolar, Marilyn, Teeter, John, Jaeger, Rudolph, Fryburg, David
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 2008
Предметы:
Pharmacokinetics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485222/
https://ncbi.nlm.nih.gov/pubmed/18477263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03122.x
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