Effects of imatinib (Glivec) on the pharmacokinetics of metoprolol, a CYP2D6 substrate, in Chinese patients with chronic myelogenous leukaemia

AIMS: To investigate the effect of imatinib on the pharmacokinetics of a CYP2D6 substrate, metoprolol, in patients with chronic myeloid leukaemia (CML). The pharmacokinetics of imatinib were also studied in these patients. METHODS: Patients (n = 20) received a single oral dose of metoprolol 100 mg o...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Wang, Yanfeng, Zhou, Li, Dutreix, Catherine, Leroy, Elisabeth, Yin, Qi, Sethuraman, Venkat, Riviere, Gilles-Jacques, Yin, Ophelia Q P, Schran, Horst, Shen, Zhi-Xiang
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2008
Fag:
Pharmacokinetics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2485214/
https://ncbi.nlm.nih.gov/pubmed/18384443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03150.x
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker