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HIV-1 Tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter

In cells infected with HIV type 1 (HIV-1), the integrated viral promoter is present in a chromatin-bound conformation and is transcriptionally silent in the absence of stimulation. The HIV-1 Tat protein binds to a stem-loop structure at the 5′ end of viral mRNA and relieves this inhibition by induci...

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Détails bibliographiques
Auteurs principaux: Marzio, Giuseppe, Tyagi, Mudit, Gutierrez, Maria Ines, Giacca, Mauro
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1998
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC24851/
https://ncbi.nlm.nih.gov/pubmed/9811832
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