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The reactive site loop of the serpin SCCA1 is essential for cysteine proteinase inhibition

The high-molecular-weight serine proteinase inhibitors (serpins) are restricted, generally, to inhibiting proteinases of the serine mechanistic class. However, the viral serpin, cytokine response modifier A, and the human serpins, antichymotrypsin and squamous cell carcinoma antigen 1 (SCCA1), inhib...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Schick, Charles, Brömme, Dieter, Bartuski, Allison J., Uemura, Yoshiki, Schechter, Norman M., Silverman, Gary A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24842/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811823/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.23.13465
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