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RAV-1 insertional mutagenesis: disruption of the c-myb locus and development of avian B-cell lymphomas.

Infection of young chickens with RAV-1, a subgroup A isolate of avian leukosis virus, results in the development of lymphoid leukosis, a B-cell lymphoma characterized by provirus insertion into the c-myc locus. We report here that when 12- to 13-day-old embryos rather than 1-day-old chickens were in...

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Detalles Bibliográficos
Main Authors: Pizer, E, Humphries, E H
Formato: Artigo
Idioma:Inglês
Publicado: 1989
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC248408/
https://ncbi.nlm.nih.gov/pubmed/2538646
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