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A DNA-tethered cleavage probe reveals the path for promoter DNA in the yeast preinitiation complex
To directly map the position of promoter DNA within the RNA Polymerase II (Pol II) transcription Preinitiation Complex (PIC), FeBABE was tethered to specific sites within the HIS4 promoter and used to map exposed surfaces of Pol II and the general transcription factors in proximity to DNA. Our resul...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2483788/ https://ncbi.nlm.nih.gov/pubmed/16819517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1117 |
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