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A DNA-tethered cleavage probe reveals the path for promoter DNA in the yeast preinitiation complex

To directly map the position of promoter DNA within the RNA Polymerase II (Pol II) transcription Preinitiation Complex (PIC), FeBABE was tethered to specific sites within the HIS4 promoter and used to map exposed surfaces of Pol II and the general transcription factors in proximity to DNA. Our resul...

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Hlavní autoři: Miller, Gail, Hahn, Steven
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483788/
https://ncbi.nlm.nih.gov/pubmed/16819517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb1117
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