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PrP(106-126) Does Not Interact with Membranes under Physiological Conditions

Transmissible spongiform encephalopathies are neurodegenerative diseases characterized by the accumulation of an abnormal isoform of the prion protein PrP(Sc). Its fragment 106-126 has been reported to maintain most of the pathological features of PrP(Sc), and a role in neurodegeneration has been pr...

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Detalhes bibliográficos
Main Authors: Henriques, Sónia Troeira, Pattenden, Leonard Keith, Aguilar, Marie-Isabel, Castanho, Miguel A. R. B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483773/
https://ncbi.nlm.nih.gov/pubmed/18469080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.131458
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