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Factors Influencing Local Membrane Curvature Induction by N-BAR Domains as Revealed by Molecular Dynamics Simulations

N-BAR domains are protein modules that bind to and induce curvature in membranes via a charged concave surface and N-terminal amphipathic helices. Recently, molecular dynamics simulations have demonstrated that the N-BAR domain can induce a strong local curvature that matches the curvature of the BA...

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Autors principals: Blood, Philip D., Swenson, Richard D., Voth, Gregory A.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483763/
https://ncbi.nlm.nih.gov/pubmed/18469070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.121160
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