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Combining identity by descent and association in genetic case-control studies

BACKGROUND: In human case-control association studies, one of the chi-square tests typically carried out is based on a 2 × 3 table of genotypes (homogeneity of three genotype frequencies in case and control individuals). We formulate the two degrees of freedom associated with a given genotype distri...

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Main Authors: Zhang, Qingrun, Wang, Shuang, Ott, Jurg
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483716/
https://ncbi.nlm.nih.gov/pubmed/18601744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-9-42
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