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Tuberculosis vaccine strain Mycobacterium bovis BCG Russia is a natural recA mutant

BACKGROUND: The current tuberculosis vaccine is a live vaccine derived from Mycobacterium bovis and attenuated by serial in vitro passaging. All vaccine substrains in use stem from one source, strain Bacille Calmette-Guérin. However, they differ in regions of genomic deletions, antigen expression le...

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Detalhes bibliográficos
Main Authors: Keller, Peter M, Böttger, Erik C, Sander, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483709/
https://ncbi.nlm.nih.gov/pubmed/18637199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-8-120
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