Phosphatidylinositol 4,5-bisphosphate regulates SNARE-dependent membrane fusion

Phosphatidylinositol 4,5-bisphosphate (PI 4,5-P(2)) on the plasma membrane is essential for vesicle exocytosis but its role in membrane fusion has not been determined. Here, we quantify the concentration of PI 4,5-P(2) as ∼6 mol% in the cytoplasmic leaflet of plasma membrane microdomains at sites of...

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Main Authors: James, Declan J., Khodthong, Chuenchanok, Kowalchyk, Judith A., Martin, Thomas F.J.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2008
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483516/
https://ncbi.nlm.nih.gov/pubmed/18644890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200801056
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