DREAM is reduced in synovial fibroblasts of patients with chronic arthritic pain: is it a suitable target for peripheral pain management?

INTRODUCTION: The endogenous pain-relieving system depends in part on the regulation of nociceptive signals through binding of opioids to the corresponding opioid receptor. Interfering with the trans-repression effect of downstream regulatory element antagonist modulator (DREAM) on the transcription...

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Autori principali: Reisch, Nataša, Engler, Andrea, Aeschlimann, André, Simmen, Beat R, Michel, Beat A, Gay, Renate E, Gay, Steffen, Sprott, Haiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483451/
https://ncbi.nlm.nih.gov/pubmed/18507845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2431
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