Molecular discrimination of responders and nonresponders to anti-TNFalpha therapy in rheumatoid arthritis by etanercept

INTRODUCTION: About 30% of rheumatoid arthritis patients fail to respond adequately to TNFα-blocking therapy. There is a medical and socioeconomic need to identify molecular markers for an early prediction of responders and nonresponders. METHODS: RNA was extracted from peripheral blood mononuclear...

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Detalhes bibliográficos
Main Authors: Koczan, Dirk, Drynda, Susanne, Hecker, Michael, Drynda, Andreas, Guthke, Reinhard, Kekow, Joern, Thiesen, Hans-Juergen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483439/
https://ncbi.nlm.nih.gov/pubmed/18454843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2419
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