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Role of calcium in substance P-induced chemokine synthesis in mouse pancreatic acinar cells

BACKGROUND AND PURPOSE: Substance P (SP) and chemokines play critical roles in acute pancreatitis. SP elevates cytosolic calcium in pancreatic acinar cells and elevated cytosolic calcium is thought to be an early event in the pathogenesis of acute pancreatitis. SP induces production of chemokines MC...

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Détails bibliographiques
Auteurs principaux: Ramnath, R D, Sun, J, Bhatia, M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483386/
https://ncbi.nlm.nih.gov/pubmed/18493246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.188
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