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Analysis of heterogeneity and epistasis in physiological mixed populations by combined structural equation modelling and latent class analysis

BACKGROUND: Biological systems are interacting, molecular networks in which genetic variation contributes to phenotypic heterogeneity. This heterogeneity is traditionally modelled as a dichotomous trait (e.g. affected vs. non-affected). This is far too simplistic considering the complexity and genet...

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Detalhes bibliográficos
Main Authors: Fenger, Mogens, Linneberg, Allan, Werge, Thomas, Jørgensen, Torben
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483291/
https://ncbi.nlm.nih.gov/pubmed/18611252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-9-43
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