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Characterization of seed nuclei in glucagon aggregation using light scattering methods and field-flow fractionation

BACKGROUND: Glucagon is a peptide hormone with many uses as a therapeutic agent, including the emergency treatment of hypoglycemia. Physical instability of glucagon in solution leads to problems with the manufacture, formulation, and delivery of this pharmaceutical product. Glucagon has been shown t...

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Bibliographic Details
Main Authors: Hoppe, Cindy C, Nguyen, Lida T, Kirsch, Lee E, Wiencek, John M
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483260/
https://ncbi.nlm.nih.gov/pubmed/18613970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1754-1611-2-10
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