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Identification of a structural determinant for resistance to β-lactam antibiotics in Gram-positive bacteria

Streptococcus pneumoniae is the main causal agent of pathologies that are increasingly resistant to antibiotic treatment. Clinical resistance of S. pneumoniae to β-lactam antibiotics is linked to multiple mutations of high molecular mass penicillin-binding proteins (H-PBPs), essential enzymes involv...

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Detalhes bibliográficos
Main Authors: Mouz, N., Gordon, E., Di Guilmi, A.-M., Petit, I., Pétillot, Y., Dupont, Y., Hakenbeck, R., Vernet, T., Dideberg, O.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24831/
https://ncbi.nlm.nih.gov/pubmed/9811812
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