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Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype

This report details the standardized experimental design and the different data streams that were collected (histopathology, clinical chemistry, hematology and gene expression from the target tissue (liver) and a bio-available tissue (blood)) after treatment with eight known hepatotoxicants (at mult...

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Bibliographic Details
Main Authors: Lobenhofer, Edward K, Auman, J Todd, Blackshear, Pamela E, Boorman, Gary A, Bushel, Pierre R, Cunningham, Michael L, Fostel, Jennifer M, Gerrish, Kevin, Heinloth, Alexandra N, Irwin, Richard D, Malarkey, David E, Merrick, B Alex, Sieber, Stella O, Tucker, Charles J, Ward, Sandra M, Wilson, Ralph E, Hurban, Patrick, Tennant, Raymond W, Paules, Richard S
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481421/
https://ncbi.nlm.nih.gov/pubmed/18570634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2008-9-6-r100
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