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The Murid Herpesvirus-4 gL Regulates an Entry-Associated Conformation Change in gH

The glycoprotein H (gH)/gL heterodimer is crucial for herpesvirus membrane fusion. Yet how it functions is not well understood. The Murid Herpesvirus-4 gH, like that of other herpesviruses, adopts its normal virion conformation by associating with gL. However, gH switched back to a gL-independent co...

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Autors principals: Gillet, Laurent, Colaco, Susanna, Stevenson, Philip G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481400/
https://ncbi.nlm.nih.gov/pubmed/18665235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002811
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