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Accumulation of Ciprofloxacin and Minocycline by Cultured Human Gingival Fibroblasts

Through a mechanism that is unclear, systemic fluoroquinolones and tetracyclines can attain higher levels in gingival fluid than in blood. We hypothesized that gingival fibroblasts take up and accumulate these agents, thereby enhancing their redistribution to the gingiva. Using fluorescence to monit...

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Autores principales: Yang, Qing, Nakkula, Robin J., Walters, John D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2481382/
https://ncbi.nlm.nih.gov/pubmed/12454098
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