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End-Point Targeted Molecular Dynamics: Large-Scale Conformational Changes in Potassium Channels

Large-scale conformational changes in proteins that happen often on biological time scales may be relatively rare events on the molecular dynamics time scale. We have implemented an approach to targeted molecular dynamics called end-point targeted molecular dynamics that transforms proteins between...

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Detalhes bibliográficos
Main Authors: Mashl, R. J., Jakobsson, E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480670/
https://ncbi.nlm.nih.gov/pubmed/18310251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.118778
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