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End-Point Targeted Molecular Dynamics: Large-Scale Conformational Changes in Potassium Channels
Large-scale conformational changes in proteins that happen often on biological time scales may be relatively rare events on the molecular dynamics time scale. We have implemented an approach to targeted molecular dynamics called end-point targeted molecular dynamics that transforms proteins between...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Biophysical Society
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2480670/ https://ncbi.nlm.nih.gov/pubmed/18310251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.118778 |
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