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Optical Lock-In Detection of FRET Using Synthetic and Genetically Encoded Optical Switches

The Förster resonance energy transfer (FRET) technique is widely used for studying protein interactions within live cells. The effectiveness and sensitivity of determining FRET, however, can be reduced by photobleaching, cross talk, autofluorescence, and unlabeled, endogenous proteins. We present a...

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Detalhes bibliográficos
Main Authors: Mao, Shu, Benninger, Richard K. P., Yan, Yuling, Petchprayoon, Chutima, Jackson, David, Easley, Christopher J., Piston, David W., Marriott, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480664/
https://ncbi.nlm.nih.gov/pubmed/18281383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.124859
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