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Expression of 14-3-3σ, P16 and P53 Proteins in Anal Squamous Intraepithelial Neoplasm and Squamous Cell Carcinoma
14-3-3σ is a p53-regulated G2/M inhibitor involved in numerous cellular signaling pathways related to cell cycle, DNA repair and apoptosis. Recent studies have showed that 14-3-3σ was silenced transcriptionally through promoter hypermethylation mainly in HPV-negative vulvar squamous cell carcinoma (...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
e-Century Publishing Corporation
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2480570/ https://ncbi.nlm.nih.gov/pubmed/18787619 |
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