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Mobility of TOAC spin-labelled peptides binding to the Src SH3 domain studied by paramagnetic NMR

Paramagnetic relaxation enhancement provides a tool for studying the dynamics as well as the structure of macromolecular complexes. The application of side-chain coupled spin-labels is limited by the mobility of the free radical. The cyclic, rigid amino acid spin-label TOAC (2,2,6,6-Tetramethylpiper...

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Autori principali: Lindfors, Hanna E., de Koning, Peter E., Drijfhout, Jan Wouter, Venezia, Brigida, Ubbink, Marcellus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480485/
https://ncbi.nlm.nih.gov/pubmed/18560762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-008-9248-0
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