Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities

Brain-derived neurotrophic factor (BDNF) has trophic effects on serotonergic (5-HT) neurons in the central nervous system. However, the role of endogenous BDNF in the development and function of these neurons has not been established in vivo because of the early postnatal lethality of BDNF null mice...

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Main Authors: Lyons, W. Ernest, Mamounas, Laura A., Ricaurte, George A., Coppola, Vincenzo, Reid, Susan W., Bora, Susan H., Wihler, Cornelia, Koliatsos, Vassilis E., Tessarollo, Lino
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24804/
https://ncbi.nlm.nih.gov/pubmed/10611369
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