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A mutant of human immunodeficiency virus with reduced RNA packaging and abnormal particle morphology.

A deletion of 30 bases was created in the noncoding region of the human immunodeficiency virus type 1 genome that extends between the 5' splice donor and the start of the gag gene. Viral particles produced after transfection of this mutant provirus had a normal protein pattern but a reduced RNA...

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Bibliographic Details
Main Authors: Clavel, F, Orenstein, J M
Format: Artigo
Language:Inglês
Published: 1990
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC248025/
https://ncbi.nlm.nih.gov/pubmed/2204725
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